K405-0555 Screening compound: 1-{5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine

K405-0555 Screening compound: 1-{5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine
K405-0555 Screening compound: 1-{5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-0555
1-{5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-0555

Molecular Formula

C23H22N4 (C23 H22 N4)

Compound Name

1-{5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine

IUPAC name

1-{57-diphenyl-7H-pyrrolo[23-d]pyrimidin-4-yl}piperidine

SMILES

C(CC1)CCN1c1ncnc2c1c(-c1ccccc1)cn2-c1ccccc1

InChI

InChI=1S/C23H22N4/c1-4-10-18(11-5-1)20-16-27(19-12-6-2-7-13-19)23-21(20)22(24-17-25-23)26-14-8-3-9-15-26/h1-2,4-7,10-13,16-17H,3,8-9,14-15H2

InChI Key

VYCJKCXDVGKDGV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04450808

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.45

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.529

Distribution Coefficient, logD

5.421

Water Solubility, LogSw

-6.08

Polar Surface Area

26.212

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

6.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

K405-0555 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K405-0555 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-0555?
Check Price and Availability of K405-0555, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-0555 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-0555
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-0555
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-0555 available by request