K405-0764 Screening compound: 7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine

K405-0764 Screening compound: 7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine
K405-0764 Screening compound: 7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-0764
7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-0764

Molecular Formula

C23H22FN5 (C23 H22 FN5)

Compound Name

7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine

IUPAC name

1-[7-(4-fluorophenyl)-5-phenyl-7H-pyrrolo[23-d]pyrimidin-4-yl]-4-methylpiperazine

SMILES

CN(CC1)CCN1c1c(c(-c2ccccc2)cn2-c(cc3)ccc3F)c2ncn1

InChI

InChI=1S/C23H22FN5/c1-27-11-13-28(14-12-27)22-21-20(17-5-3-2-4-6-17)15-29(23(21)26-16-25-22)19-9-7-18(24)8-10-19/h2-10,15-16H,11-14H2,1H3

InChI Key

BULMODKVYZUWGQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04451034

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.46

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.498

Distribution Coefficient, logD

4.034

Water Solubility, LogSw

-4.45

Polar Surface Area

29.689

Acid Dissociation Constant (pKa)

22.05

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.74

K405-0764 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K405-0764 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-0764?
Check Price and Availability of K405-0764, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-0764 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-0764
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-0764
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-0764 available by request