K405-0843 Screening compound: 1-[7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrrolidine

K405-0843 Screening compound: 1-[7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrrolidine
K405-0843 Screening compound: 1-[7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrrolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-0843
1-[7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrrolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-0843

Molecular Formula

C24H24N4O (C24 H24 N4 O)

Compound Name

1-[7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrrolidine

IUPAC name

1-[7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[23-d]pyrimidin-4-yl]pyrrolidine

SMILES

CCOc(cc1)ccc1-n1c2ncnc(N3CCCC3)c2c(-c2ccccc2)c1

InChI

InChI=1S/C24H24N4O/c1-2-29-20-12-10-19(11-13-20)28-16-21(18-8-4-3-5-9-18)22-23(25-17-26-24(22)28)27-14-6-7-15-27/h3-5,8-13,16-17H,2,6-7,14-15H2,1H3

InChI Key

VBYLMOKKPXGTEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04451121

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.603

Distribution Coefficient, logD

5.495

Water Solubility, LogSw

-5.74

Polar Surface Area

33.702

Acid Dissociation Constant (pKa)

21.17

Base Dissociation Constant (pKb)

6.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

K405-0843 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K405-0843 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-0843?
Check Price and Availability of K405-0843, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-0843 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-0843
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-0843
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-0843 available by request