K408-1103 Screening compound: 2-{4-[bis(2-methoxyethyl)sulfamoyl]benzamido}-5,5,7,7-tetramethyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxamide

K408-1103 Screening compound: 2-{4-[bis(2-methoxyethyl)sulfamoyl]benzamido}-5,5,7,7-tetramethyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxamide
K408-1103 Screening compound: 2-{4-[bis(2-methoxyethyl)sulfamoyl]benzamido}-5,5,7,7-tetramethyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K408-1103
2-{4-[bis(2-methoxyethyl)sulfamoyl]benzamido}-5,5,7,7-tetramethyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K408-1103

Molecular Formula

C25H36N4O6S2 (C25 H36 N4 O6 S2)

Compound Name

2-{4-[bis(2-methoxyethyl)sulfamoyl]benzamido}-5,5,7,7-tetramethyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxamide

IUPAC name

2-{4-[bis(2-methoxyethyl)sulfamoyl]benzamido}-5577-tetramethyl-4H5H6H7H-thieno[23-c]pyridine-3-carboxamide

SMILES

CC(C)(C1)NC(C)(C)c2c1c(C(N)=O)c(NC(c(cc1)ccc1S(N(CCOC)CCOC)(=O)=O)=O)s2

InChI

InChI=1S/C25H36N4O6S2/c1-24(2)15-18-19(21(26)30)23(36-20(18)25(3,4)28-24)27-22(31)16-7-9-17(10-8-16)37(32,33)29(11-13-34-5)12-14-35-6/h7-10,28H,11-15H2,1-6H3,(H2,26,30)(H,27,31)

InChI Key

AXFJVTATHRTCRN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05014886

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

552.72

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.421

Distribution Coefficient, logD

1.421

Water Solubility, LogSw

-2.48

Polar Surface Area

116.672

Acid Dissociation Constant (pKa)

5.35

Base Dissociation Constant (pKb)

7.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.00

K408-1103 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K408-1103 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K408-1103?
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What is the minimum amount of K408-1103 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K408-1103
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K408-1103
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K408-1103 available by request