K415-0364 Screening compound: N-{4-[5-(furan-2-yl)-1H-1,2,3-triazol-1-yl]phenyl}-5-oxo-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide

K415-0364 Screening compound: N-{4-[5-(furan-2-yl)-1H-1,2,3-triazol-1-yl]phenyl}-5-oxo-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
K415-0364 Screening compound: N-{4-[5-(furan-2-yl)-1H-1,2,3-triazol-1-yl]phenyl}-5-oxo-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K415-0364
N-{4-[5-(furan-2-yl)-1H-1,2,3-triazol-1-yl]phenyl}-5-oxo-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K415-0364

Molecular Formula

C19H14N6O3S (C19 H14 N6 O3 S)

Compound Name

N-{4-[5-(furan-2-yl)-1H-1,2,3-triazol-1-yl]phenyl}-5-oxo-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide

IUPAC name

N-{4-[5-(furan-2-yl)-1H-123-triazol-1-yl]phenyl}-5-oxo-2H3H5H-[13]thiazolo[32-a]pyrimidine-6-carboxamide

SMILES

O=C(C1=CN=C2SCCN2C1=O)Nc(cc1)ccc1-n1nncc1-c1ccco1

InChI

InChI=1S/C19H14N6O3S/c26-17(14-10-20-19-24(18(14)27)7-9-29-19)22-12-3-5-13(6-4-12)25-15(11-21-23-25)16-2-1-8-28-16/h1-6,8,10-11H,7,9H2,(H,22,26)

InChI Key

ABAIKZCFYJWETG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04440846

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.386

Distribution Coefficient, logD

0.738

Water Solubility, LogSw

-2.17

Polar Surface Area

84.000

Acid Dissociation Constant (pKa)

6.86

Base Dissociation Constant (pKb)

2.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

K415-0364 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K415-0364 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K415-0364?
Check Price and Availability of K415-0364, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K415-0364 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K415-0364
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K415-0364
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K415-0364 available by request