K600-0129 Screening compound: 6-bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)quinoline-4-carboxamide

K600-0129 Screening compound: 6-bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)quinoline-4-carboxamide
K600-0129 Screening compound: 6-bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K600-0129
6-bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K600-0129

Molecular Formula

C25H18BrFN2O (C25 H18 BrFN2 O)

Compound Name

6-bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)quinoline-4-carboxamide

IUPAC name

6-bromo-N-(23-dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)quinoline-4-carboxamide

SMILES

O=C(c1c(cc(cc2)Br)c2nc(-c(cc2)ccc2F)c1)Nc1cc(CCC2)c2cc1

InChI

InChI=1S/C25H18BrFN2O/c26-18-7-11-23-21(13-18)22(14-24(29-23)16-4-8-19(27)9-5-16)25(30)28-20-10-6-15-2-1-3-17(15)12-20/h4-14H,1-3H2,(H,28,30)

InChI Key

GTUBATAELCMBGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02088848

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.33

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.265

Distribution Coefficient, logD

7.265

Water Solubility, LogSw

-6.31

Polar Surface Area

31.675

Acid Dissociation Constant (pKa)

13.48

Base Dissociation Constant (pKb)

1.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

K600-0129 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with K600-0129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K600-0129?
Check Price and Availability of K600-0129, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K600-0129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K600-0129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K600-0129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K600-0129 available by request