K610-0288 Screening compound: 1-(3-chlorophenyl)-4-[5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine

K610-0288 Screening compound: 1-(3-chlorophenyl)-4-[5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine
K610-0288 Screening compound: 1-(3-chlorophenyl)-4-[5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K610-0288
1-(3-chlorophenyl)-4-[5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K610-0288

Molecular Formula

C26H27ClF3N5O3 (C26 H27 ClF3 N5 O3)

Compound Name

1-(3-chlorophenyl)-4-[5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine

IUPAC name

1-(3-chlorophenyl)-4-[5-(34-dimethoxyphenyl)-7-(trifluoromethyl)-4H5H6H7H-pyrazolo[15-a]pyrimidine-2-carbonyl]piperazine

SMILES

COc(ccc(C(C1)Nc2cc(C(N(CC3)CCN3c3cccc(Cl)c3)=O)nn2C1C(F)(F)F)c1)c1OC

InChI

InChI=1S/C26H27ClF3N5O3/c1-37-21-7-6-16(12-22(21)38-2)19-14-23(26(28,29)30)35-24(31-19)15-20(32-35)25(36)34-10-8-33(9-11-34)18-5-3-4-17(27)13-18/h3-7,12-13,15,19,23,31H,8-11,14H2,1-2H3

InChI Key

WIGDVKBYRRBVFG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02112754

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

549.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.614

Distribution Coefficient, logD

4.614

Water Solubility, LogSw

-4.96

Polar Surface Area

62.936

Acid Dissociation Constant (pKa)

19.56

Base Dissociation Constant (pKb)

1.57

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

38.50

K610-0288 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with K610-0288 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K610-0288?
Check Price and Availability of K610-0288, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K610-0288 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K610-0288
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K610-0288
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K610-0288 available by request