K611-0220 Screening compound: 4-amino-N-[4-(dimethylamino)phenyl]-2-({[(4-methoxyphenyl)carbamoyl]methyl}sulfanyl)-1,3-thiazole-5-carboxamide

K611-0220 Screening compound: 4-amino-N-[4-(dimethylamino)phenyl]-2-({[(4-methoxyphenyl)carbamoyl]methyl}sulfanyl)-1,3-thiazole-5-carboxamide
K611-0220 Screening compound: 4-amino-N-[4-(dimethylamino)phenyl]-2-({[(4-methoxyphenyl)carbamoyl]methyl}sulfanyl)-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K611-0220
4-amino-N-[4-(dimethylamino)phenyl]-2-({[(4-methoxyphenyl)carbamoyl]methyl}sulfanyl)-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K611-0220

Molecular Formula

C21H23N5O3S2 (C21 H23 N5 O3 S2)

Compound Name

4-amino-N-[4-(dimethylamino)phenyl]-2-({[(4-methoxyphenyl)carbamoyl]methyl}sulfanyl)-1,3-thiazole-5-carboxamide

IUPAC name

4-amino-N-[4-(dimethylamino)phenyl]-2-({[(4-methoxyphenyl)carbamoyl]methyl}sulfanyl)-13-thiazole-5-carboxamide

SMILES

CN(C)c(cc1)ccc1NC(c1c(N)nc(SCC(Nc(cc2)ccc2OC)=O)s1)=O

InChI

InChI=1S/C21H23N5O3S2/c1-26(2)15-8-4-14(5-9-15)24-20(28)18-19(22)25-21(31-18)30-12-17(27)23-13-6-10-16(29-3)11-7-13/h4-11H,12,22H2,1-3H3,(H,23,27)(H,24,28)

InChI Key

MNLBDDFCHMJAKZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02089226

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.583

Distribution Coefficient, logD

3.574

Water Solubility, LogSw

-3.96

Polar Surface Area

86.619

Acid Dissociation Constant (pKa)

12.50

Base Dissociation Constant (pKb)

9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

K611-0220 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Human Receptors Annotated Library (5376 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with K611-0220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K611-0220?
Check Price and Availability of K611-0220, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K611-0220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K611-0220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K611-0220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K611-0220 available by request