K696-0449 Screening compound: 2-(4-bromophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinazoline

K696-0449 Screening compound: 2-(4-bromophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinazoline
K696-0449 Screening compound: 2-(4-bromophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound K696-0449
2-(4-bromophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K696-0449

Molecular Formula

C24H20BrFN4 (C24 H20 BrFN4)

Compound Name

2-(4-bromophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinazoline

IUPAC name

2-(4-bromophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinazoline

SMILES

Fc(cccc1)c1N(CC1)CCN1c1nc(-c(cc2)ccc2Br)nc2ccccc12

InChI

InChI=1S/C24H20BrFN4/c25-18-11-9-17(10-12-18)23-27-21-7-3-1-5-19(21)24(28-23)30-15-13-29(14-16-30)22-8-4-2-6-20(22)26/h1-12H,13-16H2

InChI Key

WCJXVIVCGZEENN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093631

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.35

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.280

Distribution Coefficient, logD

6.695

Water Solubility, LogSw

-6.59

Polar Surface Area

24.598

Acid Dissociation Constant (pKa)

22.21

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

K696-0449 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K696-0449 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K696-0449?
Check Price and Availability of K696-0449, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K696-0449 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K696-0449
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K696-0449
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K696-0449 available by request