K784-7932 Screening compound: N-[5-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-N'-(3-methoxyphenyl)urea

K784-7932 Screening compound: N-[5-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-N'-(3-methoxyphenyl)urea
K784-7932 Screening compound: N-[5-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-N'-(3-methoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound K784-7932
N-[5-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-N'-(3-methoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K784-7932

Molecular Formula

C33H37N5O6 (C33 H37 N5 O6)

Compound Name

N-[5-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-N'-(3-methoxyphenyl)urea

IUPAC name

3-(5-{14-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-2-{6-oxo-711-diazatricyclo[7.3.1.0^{27}]trideca-24-dien-11-yl}phenyl)-1-(3-methoxyphenyl)urea

SMILES

COc1cccc(NC(Nc(cc(cc2)C(N(CC3)CCC33OCCO3)=O)c2N(CC(C2)CN34)CC2C4=CC=CC3=O)=O)c1

InChI

InChI=1S/C33H37N5O6/c1-42-26-5-2-4-25(18-26)34-32(41)35-27-17-23(31(40)36-12-10-33(11-13-36)43-14-15-44-33)8-9-29(27)37-19-22-16-24(21-37)28-6-3-7-30(39)38(28)20-22/h2-9,17-18,22,24H,10-16,19-21H2,1H3,(H2,34,35,41)

InChI Key

OUBKSVVOEUDLHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15099060

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

599.69

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

3.822

Distribution Coefficient, logD

3.822

Water Solubility, LogSw

-4.15

Polar Surface Area

89.323

Acid Dissociation Constant (pKa)

11.16

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

42.40

K784-7932 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Lipid Metabolism Library (9174 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with K784-7932 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K784-7932?
Check Price and Availability of K784-7932, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K784-7932 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K784-7932
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K784-7932
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K784-7932 available by request