K823-1681 Screening compound: ethyl 4-{[2,5-dimethyl-4-(morpholin-4-yl)thieno[2,3-d]pyrimidin-6-yl]formamido}-2-methylbutanoate

K823-1681 Screening compound: ethyl 4-{[2,5-dimethyl-4-(morpholin-4-yl)thieno[2,3-d]pyrimidin-6-yl]formamido}-2-methylbutanoate
K823-1681 Screening compound: ethyl 4-{[2,5-dimethyl-4-(morpholin-4-yl)thieno[2,3-d]pyrimidin-6-yl]formamido}-2-methylbutanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound K823-1681
ethyl 4-{[2,5-dimethyl-4-(morpholin-4-yl)thieno[2,3-d]pyrimidin-6-yl]formamido}-2-methylbutanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K823-1681

Molecular Formula

C20H28N4O4S (C20 H28 N4 O4 S)

Compound Name

ethyl 4-{[2,5-dimethyl-4-(morpholin-4-yl)thieno[2,3-d]pyrimidin-6-yl]formamido}-2-methylbutanoate

IUPAC name

ethyl 4-{[25-dimethyl-4-(morpholin-4-yl)thieno[23-d]pyrimidin-6-yl]formamido}-2-methylbutanoate

SMILES

CCOC(C(C)CCNC(c1c(C)c2c(N3CCOCC3)nc(C)nc2s1)=O)=O

InChI

InChI=1S/C20H28N4O4S/c1-5-28-20(26)12(2)6-7-21-18(25)16-13(3)15-17(24-8-10-27-11-9-24)22-14(4)23-19(15)29-16/h12H,5-11H2,1-4H3,(H,21,25)/t12-/m0/s1

InChI Key

PSATWQMFEGEMQC-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD15109641

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.848

Distribution Coefficient, logD

2.421

Water Solubility, LogSw

-3.21

Polar Surface Area

76.101

Acid Dissociation Constant (pKa)

12.96

Base Dissociation Constant (pKb)

7.62

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

60.00

K823-1681 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with K823-1681 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K823-1681?
Check Price and Availability of K823-1681, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K823-1681 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K823-1681
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K823-1681
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K823-1681 available by request