K823-1981 Screening compound: N-(2,4-difluorophenyl)-2,5-dimethyl-4-[4-(pyridin-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine-6-carboxamide

K823-1981 Screening compound: N-(2,4-difluorophenyl)-2,5-dimethyl-4-[4-(pyridin-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine-6-carboxamide
K823-1981 Screening compound: N-(2,4-difluorophenyl)-2,5-dimethyl-4-[4-(pyridin-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K823-1981
N-(2,4-difluorophenyl)-2,5-dimethyl-4-[4-(pyridin-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K823-1981

Molecular Formula

C24H22F2N6OS (C24 H22 F2 N6 OS)

Compound Name

N-(2,4-difluorophenyl)-2,5-dimethyl-4-[4-(pyridin-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(24-difluorophenyl)-25-dimethyl-4-[4-(pyridin-2-yl)piperazin-1-yl]thieno[23-d]pyrimidine-6-carboxamide

SMILES

Cc1c(C(Nc(ccc(F)c2)c2F)=O)sc2nc(C)nc(N(CC3)CCN3c3ncccc3)c12

InChI

InChI=1S/C24H22F2N6OS/c1-14-20-22(32-11-9-31(10-12-32)19-5-3-4-8-27-19)28-15(2)29-24(20)34-21(14)23(33)30-18-7-6-16(25)13-17(18)26/h3-8,13H,9-12H2,1-2H3,(H,30,33)

InChI Key

GXNJYRPXEMKQMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04422197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.241

Distribution Coefficient, logD

4.686

Water Solubility, LogSw

-5.20

Polar Surface Area

57.078

Acid Dissociation Constant (pKa)

6.99

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

K823-1981 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with K823-1981 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K823-1981?
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What is the minimum amount of K823-1981 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K823-1981
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K823-1981
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K823-1981 available by request