K841-0201 Screening compound: 2-(2-fluorophenyl)-N-(2-methoxy-5-nitrophenyl)quinazolin-4-amine

K841-0201 Screening compound: 2-(2-fluorophenyl)-N-(2-methoxy-5-nitrophenyl)quinazolin-4-amine
K841-0201 Screening compound: 2-(2-fluorophenyl)-N-(2-methoxy-5-nitrophenyl)quinazolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound K841-0201
2-(2-fluorophenyl)-N-(2-methoxy-5-nitrophenyl)quinazolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K841-0201

Molecular Formula

C21H15FN4O3 (C21 H15 FN4 O3)

Compound Name

2-(2-fluorophenyl)-N-(2-methoxy-5-nitrophenyl)quinazolin-4-amine

IUPAC name

2-(2-fluorophenyl)-N-(2-methoxy-5-nitrophenyl)quinazolin-4-amine

SMILES

COc(ccc([N+]([O-])=O)c1)c1Nc1nc(-c(cccc2)c2F)nc2ccccc12

InChI

InChI=1S/C21H15FN4O3/c1-29-19-11-10-13(26(27)28)12-18(19)24-21-15-7-3-5-9-17(15)23-20(25-21)14-6-2-4-8-16(14)22/h2-12H,1H3,(H,23,24,25)

InChI Key

SGSVVQRYVWBWEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15110566

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.37

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.061

Distribution Coefficient, logD

5.042

Water Solubility, LogSw

-4.99

Polar Surface Area

68.119

Acid Dissociation Constant (pKa)

14.28

Base Dissociation Constant (pKb)

6.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

K841-0201 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with K841-0201 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K841-0201?
Check Price and Availability of K841-0201, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K841-0201 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K841-0201
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K841-0201
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K841-0201 available by request