K937-0683 Screening compound: 2-(4-chlorophenyl)-4-{[4-(4-fluorophenyl)piperazino]carbonyl}-1(2H)-isoquinolinone

K937-0683 Screening compound: 2-(4-chlorophenyl)-4-{[4-(4-fluorophenyl)piperazino]carbonyl}-1(2H)-isoquinolinone
K937-0683 Screening compound: 2-(4-chlorophenyl)-4-{[4-(4-fluorophenyl)piperazino]carbonyl}-1(2H)-isoquinolinone alternative view

Chemical Structure Depiction of ChemDiv screening compound K937-0683
2-(4-chlorophenyl)-4-{[4-(4-fluorophenyl)piperazino]carbonyl}-1(2H)-isoquinolinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K937-0683

Molecular Formula

C26H21ClFN3O2 (C26 H21 ClFN3 O2)

Compound Name

2-(4-chlorophenyl)-4-{[4-(4-fluorophenyl)piperazino]carbonyl}-1(2H)-isoquinolinone

IUPAC name

2-(4-chlorophenyl)-4-[4-(4-fluorophenyl)piperazine-1-carbonyl]-12-dihydroisoquinolin-1-one

SMILES

O=C(C(c1c2cccc1)=CN(c(cc1)ccc1Cl)C2=O)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C26H21ClFN3O2/c27-18-5-9-21(10-6-18)31-17-24(22-3-1-2-4-23(22)26(31)33)25(32)30-15-13-29(14-16-30)20-11-7-19(28)8-12-20/h1-12,17H,13-16H2

InChI Key

ABELAJCGJUQMEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03020621

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.92

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.133

Distribution Coefficient, logD

4.133

Water Solubility, LogSw

-4.68

Polar Surface Area

35.663

Acid Dissociation Constant (pKa)

28.16

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.38

References: we are preparing a list of scientific research reports with K937-0683 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K937-0683?
Check Price and Availability of K937-0683, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K937-0683 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K937-0683
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K937-0683
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K937-0683 available by request