L008-0395 Screening compound: 4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-{[4-(propan-2-yl)phenyl]methyl}benzamide

L008-0395 Screening compound: 4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-{[4-(propan-2-yl)phenyl]methyl}benzamide
L008-0395 Screening compound: 4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-{[4-(propan-2-yl)phenyl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L008-0395
4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-{[4-(propan-2-yl)phenyl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L008-0395

Molecular Formula

C25H28N4O2 (C25 H28 N4 O2)

Compound Name

4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-{[4-(propan-2-yl)phenyl]methyl}benzamide

IUPAC name

4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-{[4-(propan-2-yl)phenyl]methyl}benzamide

SMILES

CC(C)c1ccc(CNC(c(cc2)ccc2-c(cc2)nnc2N2CCOCC2)=O)cc1

InChI

InChI=1S/C25H28N4O2/c1-18(2)20-5-3-19(4-6-20)17-26-25(30)22-9-7-21(8-10-22)23-11-12-24(28-27-23)29-13-15-31-16-14-29/h3-12,18H,13-17H2,1-2H3,(H,26,30)

InChI Key

QTYSWPJADSJWAQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27225980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.292

Distribution Coefficient, logD

4.292

Water Solubility, LogSw

-4.13

Polar Surface Area

56.948

Acid Dissociation Constant (pKa)

11.78

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L008-0395 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L008-0395 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L008-0395?
Check Price and Availability of L008-0395, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L008-0395 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L008-0395
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L008-0395
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L008-0395 available by request