L011-0486 Screening compound: 6-[3-(4-benzylpiperazine-1-carbonyl)phenyl]-N-cyclohexylpyrimidin-4-amine

L011-0486 Screening compound: 6-[3-(4-benzylpiperazine-1-carbonyl)phenyl]-N-cyclohexylpyrimidin-4-amine
L011-0486 Screening compound: 6-[3-(4-benzylpiperazine-1-carbonyl)phenyl]-N-cyclohexylpyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L011-0486
6-[3-(4-benzylpiperazine-1-carbonyl)phenyl]-N-cyclohexylpyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L011-0486

Molecular Formula

C28H33N5O (C28 H33 N5 O)

Compound Name

6-[3-(4-benzylpiperazine-1-carbonyl)phenyl]-N-cyclohexylpyrimidin-4-amine

IUPAC name

6-[3-(4-benzylpiperazine-1-carbonyl)phenyl]-N-cyclohexylpyrimidin-4-amine

SMILES

O=C(c1cc(-c2ncnc(NC3CCCCC3)c2)ccc1)N1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C28H33N5O/c34-28(33-16-14-32(15-17-33)20-22-8-3-1-4-9-22)24-11-7-10-23(18-24)26-19-27(30-21-29-26)31-25-12-5-2-6-13-25/h1,3-4,7-11,18-19,21,25H,2,5-6,12-17,20H2,(H,29,30,31)

InChI Key

YTYREORVIRUSMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27226368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.643

Distribution Coefficient, logD

4.627

Water Solubility, LogSw

-4.57

Polar Surface Area

50.493

Acid Dissociation Constant (pKa)

20.03

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

L011-0486 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L011-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L011-0486?
Check Price and Availability of L011-0486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L011-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L011-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L011-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L011-0486 available by request