L018-0251 Screening compound: N-(4-bromo-2-fluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

L018-0251 Screening compound: N-(4-bromo-2-fluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide
L018-0251 Screening compound: N-(4-bromo-2-fluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L018-0251
N-(4-bromo-2-fluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L018-0251

Molecular Formula

C21H20BrFN4O (C21 H20 BrFN4 O)

Compound Name

N-(4-bromo-2-fluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

IUPAC name

N-(4-bromo-2-fluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(cc1)ncc1-n1cccc1)Nc(ccc(Br)c1)c1F

InChI

InChI=1S/C21H20BrFN4O/c22-16-3-5-19(18(23)13-16)25-21(28)15-7-11-27(12-8-15)20-6-4-17(14-24-20)26-9-1-2-10-26/h1-6,9-10,13-15H,7-8,11-12H2,(H,25,28)

InChI Key

SORMEVLOWHCZTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15116417

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.32

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.936

Distribution Coefficient, logD

4.893

Water Solubility, LogSw

-4.67

Polar Surface Area

38.671

Acid Dissociation Constant (pKa)

8.39

Base Dissociation Constant (pKb)

4.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L018-0251 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L018-0251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L018-0251?
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What is the minimum amount of L018-0251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L018-0251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L018-0251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L018-0251 available by request