L054-0387 Screening compound: [4-(1-benzyl-1H-1,3-benzimidazol-2-yl)piperazino][2-(trifluoromethyl)phenyl]methanone

L054-0387 Screening compound: [4-(1-benzyl-1H-1,3-benzimidazol-2-yl)piperazino][2-(trifluoromethyl)phenyl]methanone
L054-0387 Screening compound: [4-(1-benzyl-1H-1,3-benzimidazol-2-yl)piperazino][2-(trifluoromethyl)phenyl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L054-0387
[4-(1-benzyl-1H-1,3-benzimidazol-2-yl)piperazino][2-(trifluoromethyl)phenyl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L054-0387

Molecular Formula

C26H23F3N4O (C26 H23 F3 N4 O)

Compound Name

[4-(1-benzyl-1H-1,3-benzimidazol-2-yl)piperazino][2-(trifluoromethyl)phenyl]methanone

IUPAC name

n/a

SMILES

O=C(c1c(C(F)(F)F)cccc1)N(CC1)CCN1c1nc(cccc2)c2n1Cc1ccccc1

InChI

InChI=1S/C26H23F3N4O/c27-26(28,29)21-11-5-4-10-20(21)24(34)31-14-16-32(17-15-31)25-30-22-12-6-7-13-23(22)33(25)18-19-8-2-1-3-9-19/h1-13H,14-18H2

InChI Key

SFXXNBCRNVRSSK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15117013

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.270

Distribution Coefficient, logD

5.237

Water Solubility, LogSw

-5.49

Polar Surface Area

29.616

Acid Dissociation Constant (pKa)

22.97

Base Dissociation Constant (pKb)

6.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

L054-0387 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with L054-0387 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L054-0387?
Check Price and Availability of L054-0387, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L054-0387 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L054-0387
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L054-0387
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L054-0387 available by request