L075-0981 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-(piperidin-1-yl)ethan-1-one

L075-0981 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-(piperidin-1-yl)ethan-1-one
L075-0981 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-(piperidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L075-0981
2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-(piperidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L075-0981

Molecular Formula

C21H26ClN3O2 (C21 H26 ClN3 O2)

Compound Name

2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-(piperidin-1-yl)ethan-1-one

IUPAC name

2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-(piperidin-1-yl)ethan-1-one

SMILES

O=C(CC(CC1)CCN1C(c1cc(cc(cc2)Cl)c2[nH]1)=O)N1CCCCC1

InChI

InChI=1S/C21H26ClN3O2/c22-17-4-5-18-16(13-17)14-19(23-18)21(27)25-10-6-15(7-11-25)12-20(26)24-8-2-1-3-9-24/h4-5,13-15,23H,1-3,6-12H2

InChI Key

WOOYVZHJWKYJKI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15117859

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.91

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.036

Distribution Coefficient, logD

4.036

Water Solubility, LogSw

-4.33

Polar Surface Area

42.357

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

0.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.40

L075-0981 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L075-0981 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L075-0981?
Check Price and Availability of L075-0981, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L075-0981 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L075-0981
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L075-0981
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L075-0981 available by request