L097-0378 Screening compound: 1-(2-fluorophenyl)-4-[2-(pyridin-3-yl)-1,3-thiazole-4-carbonyl]piperazine

L097-0378 Screening compound: 1-(2-fluorophenyl)-4-[2-(pyridin-3-yl)-1,3-thiazole-4-carbonyl]piperazine
L097-0378 Screening compound: 1-(2-fluorophenyl)-4-[2-(pyridin-3-yl)-1,3-thiazole-4-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L097-0378
1-(2-fluorophenyl)-4-[2-(pyridin-3-yl)-1,3-thiazole-4-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L097-0378

Molecular Formula

C19H17FN4OS (C19 H17 FN4 OS)

Compound Name

1-(2-fluorophenyl)-4-[2-(pyridin-3-yl)-1,3-thiazole-4-carbonyl]piperazine

IUPAC name

1-(2-fluorophenyl)-4-[2-(pyridin-3-yl)-13-thiazole-4-carbonyl]piperazine

SMILES

O=C(c1csc(-c2cnccc2)n1)N(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C19H17FN4OS/c20-15-5-1-2-6-17(15)23-8-10-24(11-9-23)19(25)16-13-26-18(22-16)14-4-3-7-21-12-14/h1-7,12-13H,8-11H2

InChI Key

BCCXQUOXTUZZME-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27232073

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.037

Distribution Coefficient, logD

3.024

Water Solubility, LogSw

-3.08

Polar Surface Area

39.098

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

5.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

L097-0378 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L097-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L097-0378?
Check Price and Availability of L097-0378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L097-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L097-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L097-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L097-0378 available by request