L106-0291 Screening compound: 3-(2-bromophenyl)-5-[(2,4,6-trimethylbenzenesulfonyl)methyl]-1,2,4-oxadiazole

L106-0291 Screening compound: 3-(2-bromophenyl)-5-[(2,4,6-trimethylbenzenesulfonyl)methyl]-1,2,4-oxadiazole
L106-0291 Screening compound: 3-(2-bromophenyl)-5-[(2,4,6-trimethylbenzenesulfonyl)methyl]-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L106-0291
3-(2-bromophenyl)-5-[(2,4,6-trimethylbenzenesulfonyl)methyl]-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L106-0291

Molecular Formula

C18H17BrN2O3S (C18 H17 BrN2 O3 S)

Compound Name

3-(2-bromophenyl)-5-[(2,4,6-trimethylbenzenesulfonyl)methyl]-1,2,4-oxadiazole

IUPAC name

3-(2-bromophenyl)-5-[(246-trimethylbenzenesulfonyl)methyl]-124-oxadiazole

SMILES

Cc(cc1C)cc(C)c1S(Cc1nc(-c(cccc2)c2Br)no1)(=O)=O

InChI

InChI=1S/C18H17BrN2O3S/c1-11-8-12(2)17(13(3)9-11)25(22,23)10-16-20-18(21-24-16)14-6-4-5-7-15(14)19/h4-9H,10H2,1-3H3

InChI Key

GQUFEUDXMDTBSC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27232522

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.31

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.774

Distribution Coefficient, logD

4.774

Water Solubility, LogSw

-4.63

Polar Surface Area

60.346

Acid Dissociation Constant (pKa)

21.35

Base Dissociation Constant (pKb)

-7.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L106-0291 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L106-0291 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L106-0291?
Check Price and Availability of L106-0291, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L106-0291 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L106-0291
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L106-0291
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L106-0291 available by request