L150-0020 Screening compound: N-{5-[(5-ethyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}-N'-(4-fluorophenyl)urea

L150-0020 Screening compound: N-{5-[(5-ethyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}-N'-(4-fluorophenyl)urea
L150-0020 Screening compound: N-{5-[(5-ethyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}-N'-(4-fluorophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L150-0020
N-{5-[(5-ethyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}-N'-(4-fluorophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L150-0020

Molecular Formula

C16H13FN8OS2 (C16 H13 FN8 OS2)

Compound Name

N-{5-[(5-ethyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-1,3,4-thiadiazol-2-yl}-N'-(4-fluorophenyl)urea

IUPAC name

3-[5-({5-ethyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)-134-thiadiazol-2-yl]-1-(4-fluorophenyl)urea

SMILES

CCc1nc2ncnn2c(Sc2nnc(NC(Nc(cc3)ccc3F)=O)s2)c1

InChI

InChI=1S/C16H13FN8OS2/c1-2-10-7-12(25-13(20-10)18-8-19-25)27-16-24-23-15(28-16)22-14(26)21-11-5-3-9(17)4-6-11/h3-8H,2H2,1H3,(H2,21,22,23,26)

InChI Key

HYMCFUKASMPWOA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27234317

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.206

Distribution Coefficient, logD

4.206

Water Solubility, LogSw

-4.17

Polar Surface Area

87.647

Acid Dissociation Constant (pKa)

10.89

Base Dissociation Constant (pKb)

3.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

L150-0020 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L150-0020 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L150-0020?
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What is the minimum amount of L150-0020 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L150-0020
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L150-0020
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L150-0020 available by request