L155-0080 Screening compound: 2-{4-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-methylpyrimidine

L155-0080 Screening compound: 2-{4-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-methylpyrimidine
L155-0080 Screening compound: 2-{4-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-methylpyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L155-0080
2-{4-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-methylpyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L155-0080

Molecular Formula

C23H31N5O (C23 H31 N5 O)

Compound Name

2-{4-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-methylpyrimidine

IUPAC name

2-{4-[4-(23-dimethylphenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-methylpyrimidine

SMILES

Cc1cccc(N(CC2)CCN2C(C(CC2)CCN2c2nc(C)ccn2)=O)c1C

InChI

InChI=1S/C23H31N5O/c1-17-5-4-6-21(19(17)3)26-13-15-27(16-14-26)22(29)20-8-11-28(12-9-20)23-24-10-7-18(2)25-23/h4-7,10,20H,8-9,11-16H2,1-3H3

InChI Key

KHGJAQSWTFDQEH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27234958

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.878

Distribution Coefficient, logD

3.877

Water Solubility, LogSw

-3.88

Polar Surface Area

41.035

Acid Dissociation Constant (pKa)

19.29

Base Dissociation Constant (pKb)

10.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

L155-0080 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L155-0080 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L155-0080?
Check Price and Availability of L155-0080, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L155-0080 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L155-0080
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L155-0080
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L155-0080 available by request