L221-1263 Screening compound: (3-methylphenyl)[4-(2-thienyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl]methanone

L221-1263 Screening compound: (3-methylphenyl)[4-(2-thienyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl]methanone
L221-1263 Screening compound: (3-methylphenyl)[4-(2-thienyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L221-1263
(3-methylphenyl)[4-(2-thienyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L221-1263

Molecular Formula

C24H20N2OS (C24 H20 N2 OS)

Compound Name

(3-methylphenyl)[4-(2-thienyl)-4H-pyrrolo[1,2-a][1,4]benzodiazepin-5(6H)-yl]methanone

IUPAC name

8-(3-methylbenzoyl)-7-(thiophen-2-yl)-28-diazatricyclo[8.4.0.0^{26}]tetradeca-1(10)351113-pentaene

SMILES

Cc1cccc(C(N(Cc(cccc2)c2-n2c3ccc2)C3c2cccs2)=O)c1

InChI

InChI=1S/C24H20N2OS/c1-17-7-4-9-18(15-17)24(27)26-16-19-8-2-3-10-20(19)25-13-5-11-21(25)23(26)22-12-6-14-28-22/h2-15,23H,16H2,1H3/t23-/m0/s1

InChI Key

MZQBLGJGQQNMFJ-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD15120428

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.5

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.508

Distribution Coefficient, logD

5.508

Water Solubility, LogSw

-5.49

Polar Surface Area

18.769

Acid Dissociation Constant (pKa)

26.77

Base Dissociation Constant (pKb)

-4.14

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

L221-1263 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L221-1263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L221-1263?
Check Price and Availability of L221-1263, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L221-1263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L221-1263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L221-1263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L221-1263 available by request