L226-1028 Screening compound: 2-methoxy-1-[4-(3-methylphenyl)-7,8,9,10-tetrahydro-4H-[1]benzothieno[3,2-f]pyrrolo[1,2-a][1,4]diazepin-5(6H)-yl]-1-ethanone

L226-1028 Screening compound: 2-methoxy-1-[4-(3-methylphenyl)-7,8,9,10-tetrahydro-4H-[1]benzothieno[3,2-f]pyrrolo[1,2-a][1,4]diazepin-5(6H)-yl]-1-ethanone
L226-1028 Screening compound: 2-methoxy-1-[4-(3-methylphenyl)-7,8,9,10-tetrahydro-4H-[1]benzothieno[3,2-f]pyrrolo[1,2-a][1,4]diazepin-5(6H)-yl]-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L226-1028
2-methoxy-1-[4-(3-methylphenyl)-7,8,9,10-tetrahydro-4H-[1]benzothieno[3,2-f]pyrrolo[1,2-a][1,4]diazepin-5(6H)-yl]-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L226-1028

Molecular Formula

C24H26N2O2S (C24 H26 N2 O2 S)

Compound Name

2-methoxy-1-[4-(3-methylphenyl)-7,8,9,10-tetrahydro-4H-[1]benzothieno[3,2-f]pyrrolo[1,2-a][1,4]diazepin-5(6H)-yl]-1-ethanone

IUPAC name

2-methoxy-1-[7-(3-methylphenyl)-17-thia-28-diazatetracyclo[8.7.0.0^{26}.0^{1116}]heptadeca-1(10)3511(16)-tetraen-8-yl]ethan-1-one

SMILES

Cc1cccc(C(c2cccn2-c2c(C3)c(CCCC4)c4s2)N3C(COC)=O)c1

InChI

InChI=1S/C24H26N2O2S/c1-16-7-5-8-17(13-16)23-20-10-6-12-25(20)24-19(14-26(23)22(27)15-28-2)18-9-3-4-11-21(18)29-24/h5-8,10,12-13,23H,3-4,9,11,14-15H2,1-2H3/t23-/m0/s1

InChI Key

SPCLZEPZKNFIEK-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27236419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.55

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.418

Distribution Coefficient, logD

5.418

Water Solubility, LogSw

-5.29

Polar Surface Area

26.290

Acid Dissociation Constant (pKa)

21.24

Base Dissociation Constant (pKb)

-3.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

L226-1028 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Developmental Pathway (Hh/Wnt) Set (2238 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Others
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L226-1028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L226-1028?
Check Price and Availability of L226-1028, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L226-1028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L226-1028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L226-1028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L226-1028 available by request