L228-0847 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}azepane

L228-0847 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}azepane
L228-0847 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}azepane alternative view

Chemical Structure Depiction of ChemDiv screening compound L228-0847
1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}azepane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L228-0847

Molecular Formula

C17H22N2O3S2 (C17 H22 N2 O3 S2)

Compound Name

1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}azepane

IUPAC name

1-{[5-(2-cyclobutyl-13-oxazol-5-yl)thiophen-2-yl]sulfonyl}azepane

SMILES

O=S(c1ccc(-c2cnc(C3CCC3)o2)s1)(N1CCCCCC1)=O

InChI

InChI=1S/C17H22N2O3S2/c20-24(21,19-10-3-1-2-4-11-19)16-9-8-15(23-16)14-12-18-17(22-14)13-6-5-7-13/h8-9,12-13H,1-7,10-11H2

InChI Key

DBYYMEMTUWTESM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236857

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.938

Distribution Coefficient, logD

3.938

Water Solubility, LogSw

-3.77

Polar Surface Area

51.274

Acid Dissociation Constant (pKa)

26.96

Base Dissociation Constant (pKb)

3.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.80

L228-0847 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L228-0847 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L228-0847?
Check Price and Availability of L228-0847, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L228-0847 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L228-0847
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L228-0847
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L228-0847 available by request