L228-0873 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

L228-0873 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline
L228-0873 Screening compound: 1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L228-0873
1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L228-0873

Molecular Formula

C20H20N2O3S2 (C20 H20 N2 O3 S2)

Compound Name

1-{[5-(2-cyclobutyl-1,3-oxazol-5-yl)thiophen-2-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

IUPAC name

1-{[5-(2-cyclobutyl-13-oxazol-5-yl)thiophen-2-yl]sulfonyl}-1234-tetrahydroquinoline

SMILES

O=S(c1ccc(-c2cnc(C3CCC3)o2)s1)(N(CCC1)c2c1cccc2)=O

InChI

InChI=1S/C20H20N2O3S2/c23-27(24,22-12-4-8-14-5-1-2-9-16(14)22)19-11-10-18(26-19)17-13-21-20(25-17)15-6-3-7-15/h1-2,5,9-11,13,15H,3-4,6-8,12H2

InChI Key

MUARPHIBQGOHEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27236872

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.273

Distribution Coefficient, logD

4.273

Water Solubility, LogSw

-4.20

Polar Surface Area

50.384

Acid Dissociation Constant (pKa)

24.75

Base Dissociation Constant (pKb)

3.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

L228-0873 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Others

References: we are preparing a list of scientific research reports with L228-0873 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L228-0873?
Check Price and Availability of L228-0873, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L228-0873 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L228-0873
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L228-0873
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L228-0873 available by request