L234-1148 Screening compound: 3-[4-(4-fluorophenoxy)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole

L234-1148 Screening compound: 3-[4-(4-fluorophenoxy)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole
L234-1148 Screening compound: 3-[4-(4-fluorophenoxy)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L234-1148
3-[4-(4-fluorophenoxy)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L234-1148

Molecular Formula

C23H19FN2O5 (C23 H19 FN2 O5)

Compound Name

3-[4-(4-fluorophenoxy)phenyl]-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole

IUPAC name

3-[4-(4-fluorophenoxy)phenyl]-5-(345-trimethoxyphenyl)-124-oxadiazole

SMILES

COc1cc(-c2nc(-c(cc3)ccc3Oc(cc3)ccc3F)no2)cc(OC)c1OC

InChI

InChI=1S/C23H19FN2O5/c1-27-19-12-15(13-20(28-2)21(19)29-3)23-25-22(26-31-23)14-4-8-17(9-5-14)30-18-10-6-16(24)7-11-18/h4-13H,1-3H3

InChI Key

WAWBQRQGWVRFAC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27237629

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.537

Distribution Coefficient, logD

5.537

Water Solubility, LogSw

-5.62

Polar Surface Area

61.370

Acid Dissociation Constant (pKa)

32.86

Base Dissociation Constant (pKb)

-3.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

L234-1148 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L234-1148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L234-1148?
Check Price and Availability of L234-1148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L234-1148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L234-1148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L234-1148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L234-1148 available by request