L258-0423 Screening compound: 1-{2-[1-(4-fluorobenzenesulfonyl)piperidin-4-yl]ethyl}-3-(2-methylpropyl)urea

L258-0423 Screening compound: 1-{2-[1-(4-fluorobenzenesulfonyl)piperidin-4-yl]ethyl}-3-(2-methylpropyl)urea
L258-0423 Screening compound: 1-{2-[1-(4-fluorobenzenesulfonyl)piperidin-4-yl]ethyl}-3-(2-methylpropyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L258-0423
1-{2-[1-(4-fluorobenzenesulfonyl)piperidin-4-yl]ethyl}-3-(2-methylpropyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L258-0423

Molecular Formula

C18H28FN3O3S (C18 H28 FN3 O3 S)

Compound Name

1-{2-[1-(4-fluorobenzenesulfonyl)piperidin-4-yl]ethyl}-3-(2-methylpropyl)urea

IUPAC name

1-{2-[1-(4-fluorobenzenesulfonyl)piperidin-4-yl]ethyl}-3-(2-methylpropyl)urea

SMILES

CC(C)CNC(NCCC(CC1)CCN1S(c(cc1)ccc1F)(=O)=O)=O

InChI

InChI=1S/C18H28FN3O3S/c1-14(2)13-21-18(23)20-10-7-15-8-11-22(12-9-15)26(24,25)17-5-3-16(19)4-6-17/h3-6,14-15H,7-13H2,1-2H3,(H2,20,21,23)

InChI Key

HNZIIEOBOGBWCP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27238548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.883

Distribution Coefficient, logD

2.883

Water Solubility, LogSw

-3.52

Polar Surface Area

67.010

Acid Dissociation Constant (pKa)

15.49

Base Dissociation Constant (pKb)

1.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.10

L258-0423 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with L258-0423 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L258-0423?
Check Price and Availability of L258-0423, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L258-0423 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L258-0423
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L258-0423
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L258-0423 available by request