L261-0538 Screening compound: (E)-N-(3,4-dimethoxyphenyl)-N'-(3,5-dimethylphenyl)-N''-methanesulfonylguanidine

L261-0538 Screening compound: (E)-N-(3,4-dimethoxyphenyl)-N'-(3,5-dimethylphenyl)-N''-methanesulfonylguanidine
L261-0538 Screening compound: (E)-N-(3,4-dimethoxyphenyl)-N'-(3,5-dimethylphenyl)-N''-methanesulfonylguanidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L261-0538
(E)-N-(3,4-dimethoxyphenyl)-N'-(3,5-dimethylphenyl)-N''-methanesulfonylguanidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L261-0538

Molecular Formula

C18H23N3O4S (C18 H23 N3 O4 S)

Compound Name

(E)-N-(3,4-dimethoxyphenyl)-N'-(3,5-dimethylphenyl)-N''-methanesulfonylguanidine

IUPAC name

(E)-N-(34-dimethoxyphenyl)-N'-(35-dimethylphenyl)-N''-methanesulfonylguanidine

SMILES

Cc1cc(N/C(/Nc(cc2)cc(OC)c2OC)=N\S(C)(=O)=O)cc(C)c1

InChI

InChI=1S/C18H23N3O4S/c1-12-8-13(2)10-15(9-12)20-18(21-26(5,22)23)19-14-6-7-16(24-3)17(11-14)25-4/h6-11H,1-5H3,(H2,19,20,21)

InChI Key

KMULNMQSNUAJRR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15121318

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.162

Distribution Coefficient, logD

3.162

Water Solubility, LogSw

-3.41

Polar Surface Area

74.309

Acid Dissociation Constant (pKa)

13.67

Base Dissociation Constant (pKb)

3.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

L261-0538 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Nuclear receptors
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L261-0538 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L261-0538?
Check Price and Availability of L261-0538, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L261-0538 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L261-0538
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L261-0538
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L261-0538 available by request