L271-0296 Screening compound: 4-[2-(4-fluorophenyl)acetyl]-N-[5-(morpholinosulfonyl)-2-thienyl]-1,4-diazepane-1-carboxamide

L271-0296 Screening compound: 4-[2-(4-fluorophenyl)acetyl]-N-[5-(morpholinosulfonyl)-2-thienyl]-1,4-diazepane-1-carboxamide
L271-0296 Screening compound: 4-[2-(4-fluorophenyl)acetyl]-N-[5-(morpholinosulfonyl)-2-thienyl]-1,4-diazepane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L271-0296
4-[2-(4-fluorophenyl)acetyl]-N-[5-(morpholinosulfonyl)-2-thienyl]-1,4-diazepane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L271-0296

Molecular Formula

C22H27FN4O5S2 (C22 H27 FN4 O5 S2)

Compound Name

4-[2-(4-fluorophenyl)acetyl]-N-[5-(morpholinosulfonyl)-2-thienyl]-1,4-diazepane-1-carboxamide

IUPAC name

4-[2-(4-fluorophenyl)acetyl]-N-[5-(morpholine-4-sulfonyl)thiophen-2-yl]-14-diazepane-1-carboxamide

SMILES

O=C(Cc(cc1)ccc1F)N(CCC1)CCN1C(Nc(s1)ccc1S(N1CCOCC1)(=O)=O)=O

InChI

InChI=1S/C22H27FN4O5S2/c23-18-4-2-17(3-5-18)16-20(28)25-8-1-9-26(11-10-25)22(29)24-19-6-7-21(33-19)34(30,31)27-12-14-32-15-13-27/h2-7H,1,8-16H2,(H,24,29)

InChI Key

YRFPXLBHXPRZSJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

510.61

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.951

Distribution Coefficient, logD

1.951

Water Solubility, LogSw

-2.67

Polar Surface Area

82.079

Acid Dissociation Constant (pKa)

10.45

Base Dissociation Constant (pKb)

1.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.46

L271-0296 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L271-0296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L271-0296?
Check Price and Availability of L271-0296, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L271-0296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L271-0296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L271-0296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L271-0296 available by request