L275-0109 Screening compound: 1-methyl-5-(pyrrolidine-1-carbonyl)-2-{[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole

L275-0109 Screening compound: 1-methyl-5-(pyrrolidine-1-carbonyl)-2-{[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole
L275-0109 Screening compound: 1-methyl-5-(pyrrolidine-1-carbonyl)-2-{[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L275-0109
1-methyl-5-(pyrrolidine-1-carbonyl)-2-{[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L275-0109

Molecular Formula

C23H27N5O2S (C23 H27 N5 O2 S)

Compound Name

1-methyl-5-(pyrrolidine-1-carbonyl)-2-{[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole

IUPAC name

1-methyl-5-(pyrrolidine-1-carbonyl)-2-{[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl}-1H-13-benzodiazole

SMILES

Cn1c(ccc(C(N2CCCC2)=O)c2)c2nc1CN(CC1)CCN1C(c1cccs1)=O

InChI

InChI=1S/C23H27N5O2S/c1-25-19-7-6-17(22(29)27-8-2-3-9-27)15-18(19)24-21(25)16-26-10-12-28(13-11-26)23(30)20-5-4-14-31-20/h4-7,14-15H,2-3,8-13,16H2,1H3

InChI Key

BCPHJELBZJDRAC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.840

Distribution Coefficient, logD

1.395

Water Solubility, LogSw

-2.41

Polar Surface Area

50.446

Acid Dissociation Constant (pKa)

26.49

Base Dissociation Constant (pKb)

7.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

L275-0109 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L275-0109 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L275-0109?
Check Price and Availability of L275-0109, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L275-0109 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L275-0109
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L275-0109
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L275-0109 available by request