L281-0110 Screening compound: N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]cyclopropanecarboxamide

L281-0110 Screening compound: N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]cyclopropanecarboxamide
L281-0110 Screening compound: N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L281-0110
N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L281-0110

Molecular Formula

C17H17N5OS (C17 H17 N5 OS)

Compound Name

N-[4-({5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)phenyl]cyclopropanecarboxamide

IUPAC name

N-[4-({56-dimethyl-[124]triazolo[15-a]pyrimidin-7-yl}sulfanyl)phenyl]cyclopropanecarboxamide

SMILES

Cc(c(C)nc1ncnn11)c1Sc(cc1)ccc1NC(C1CC1)=O

InChI

InChI=1S/C17H17N5OS/c1-10-11(2)20-17-18-9-19-22(17)16(10)24-14-7-5-13(6-8-14)21-15(23)12-3-4-12/h5-9,12H,3-4H2,1-2H3,(H,21,23)

InChI Key

HOYSBSKSGIWYDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122530

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.047

Distribution Coefficient, logD

3.047

Water Solubility, LogSw

-3.35

Polar Surface Area

55.910

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

3.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L281-0110 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Agro:
  • Agro
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L281-0110 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L281-0110?
Check Price and Availability of L281-0110, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L281-0110 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L281-0110
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L281-0110
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L281-0110 available by request