L286-0117 Screening compound: 1-{2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine

L286-0117 Screening compound: 1-{2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine
L286-0117 Screening compound: 1-{2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound L286-0117
1-{2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L286-0117

Molecular Formula

C25H26N4O4S (C25 H26 N4 O4 S)

Compound Name

1-{2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine

IUPAC name

1-{2-methyl-5-[5-(pyrrolidine-1-carbonyl)-124-oxadiazol-3-yl]benzenesulfonyl}-4-phenyl-1236-tetrahydropyridine

SMILES

Cc(ccc(-c1noc(C(N2CCCC2)=O)n1)c1)c1S(N(CC1)CC=C1c1ccccc1)(=O)=O

InChI

InChI=1S/C25H26N4O4S/c1-18-9-10-21(23-26-24(33-27-23)25(30)28-13-5-6-14-28)17-22(18)34(31,32)29-15-11-20(12-16-29)19-7-3-2-4-8-19/h2-4,7-11,17H,5-6,12-16H2,1H3

InChI Key

OVTXPJXBQCURDC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240425

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.856

Distribution Coefficient, logD

4.856

Water Solubility, LogSw

-4.61

Polar Surface Area

80.369

Acid Dissociation Constant (pKa)

26.27

Base Dissociation Constant (pKb)

-4.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L286-0117 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L286-0117 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L286-0117?
Check Price and Availability of L286-0117, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L286-0117 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L286-0117
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L286-0117
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L286-0117 available by request