L286-1265 Screening compound: 2-{2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-1,2,3,4-tetrahydroisoquinoline

L286-1265 Screening compound: 2-{2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-1,2,3,4-tetrahydroisoquinoline
L286-1265 Screening compound: 2-{2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L286-1265
2-{2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L286-1265

Molecular Formula

C23H24N4O5S (C23 H24 N4 O5 S)

Compound Name

2-{2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{2-methyl-5-[5-(morpholine-4-carbonyl)-124-oxadiazol-3-yl]benzenesulfonyl}-1234-tetrahydroisoquinoline

SMILES

Cc(ccc(-c1noc(C(N2CCOCC2)=O)n1)c1)c1S(N(CC1)Cc2c1cccc2)(=O)=O

InChI

InChI=1S/C23H24N4O5S/c1-16-6-7-18(21-24-22(32-25-21)23(28)26-10-12-31-13-11-26)14-20(16)33(29,30)27-9-8-17-4-2-3-5-19(17)15-27/h2-7,14H,8-13,15H2,1H3

InChI Key

CANJWVWUKIZFRT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27240598

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.53

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.342

Distribution Coefficient, logD

3.342

Water Solubility, LogSw

-3.57

Polar Surface Area

87.845

Acid Dissociation Constant (pKa)

25.79

Base Dissociation Constant (pKb)

-4.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L286-1265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L286-1265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L286-1265?
Check Price and Availability of L286-1265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L286-1265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L286-1265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L286-1265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L286-1265 available by request