L287-0077 Screening compound: 4-(5-methyl-1,2,4-oxadiazol-3-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

L287-0077 Screening compound: 4-(5-methyl-1,2,4-oxadiazol-3-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide
L287-0077 Screening compound: 4-(5-methyl-1,2,4-oxadiazol-3-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-0077
4-(5-methyl-1,2,4-oxadiazol-3-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-0077

Molecular Formula

C13H12N4O5S3 (C13 H12 N4 O5 S3)

Compound Name

4-(5-methyl-1,2,4-oxadiazol-3-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

IUPAC name

4-(5-methyl-124-oxadiazol-3-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

SMILES

Cc1nc(-c2csc(S(Nc(cc3)ccc3S(N)(=O)=O)(=O)=O)c2)no1

InChI

InChI=1S/C13H12N4O5S3/c1-8-15-13(16-22-8)9-6-12(23-7-9)25(20,21)17-10-2-4-11(5-3-10)24(14,18)19/h2-7,17H,1H3,(H2,14,18,19)

InChI Key

NPWRRUUNSNCVQZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15122821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.46

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.494

Distribution Coefficient, logD

1.196

Water Solubility, LogSw

-2.38

Polar Surface Area

123.415

Acid Dissociation Constant (pKa)

7.40

Base Dissociation Constant (pKb)

-2.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.70

L287-0077 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L287-0077 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-0077?
Check Price and Availability of L287-0077, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-0077 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-0077
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-0077
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-0077 available by request