L287-2505 Screening compound: 2-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

L287-2505 Screening compound: 2-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole
L287-2505 Screening compound: 2-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound L287-2505
2-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L287-2505

Molecular Formula

C23H23N5O4S2 (C23 H23 N5 O4 S2)

Compound Name

2-(4-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

IUPAC name

2-(4-{[4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperazine-1-carbonyl)-1H-indole

SMILES

O=C(c1cc(cccc2)c2[nH]1)N(CC1)CCN1S(c1cc(-c2noc(C3CCC3)n2)cs1)(=O)=O

InChI

InChI=1S/C23H23N5O4S2/c29-23(19-12-16-4-1-2-7-18(16)24-19)27-8-10-28(11-9-27)34(30,31)20-13-17(14-33-20)21-25-22(32-26-21)15-5-3-6-15/h1-2,4,7,12-15,24H,3,5-6,8-11H2

InChI Key

VTDQRYCYWFGXNE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241000

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.6

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.168

Distribution Coefficient, logD

4.168

Water Solubility, LogSw

-4.25

Polar Surface Area

90.702

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

-2.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L287-2505 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with L287-2505 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L287-2505?
Check Price and Availability of L287-2505, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L287-2505 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L287-2505
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L287-2505
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L287-2505 available by request