L288-0179 Screening compound: 3-(3-methyl-1-benzofuran-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

L288-0179 Screening compound: 3-(3-methyl-1-benzofuran-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide
L288-0179 Screening compound: 3-(3-methyl-1-benzofuran-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L288-0179
3-(3-methyl-1-benzofuran-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L288-0179

Molecular Formula

C20H18N4O5S (C20 H18 N4 O5 S)

Compound Name

3-(3-methyl-1-benzofuran-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]-1,2,4-oxadiazole-5-carboxamide

IUPAC name

3-(3-methyl-1-benzofuran-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]-124-oxadiazole-5-carboxamide

SMILES

Cc1c(-c2noc(C(NCCc(cc3)ccc3S(N)(=O)=O)=O)n2)oc2c1cccc2

InChI

InChI=1S/C20H18N4O5S/c1-12-15-4-2-3-5-16(15)28-17(12)18-23-20(29-24-18)19(25)22-11-10-13-6-8-14(9-7-13)30(21,26)27/h2-9H,10-11H2,1H3,(H,22,25)(H2,21,26,27)

InChI Key

QCIOXDOJLHCXCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241024

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.45

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.371

Distribution Coefficient, logD

2.371

Water Solubility, LogSw

-2.86

Polar Surface Area

115.300

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

-2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

L288-0179 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Antibacterial Compounds Library (13827 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L288-0179 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L288-0179?
Check Price and Availability of L288-0179, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L288-0179 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L288-0179
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L288-0179
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L288-0179 available by request