L303-3183 Screening compound: 1-(4-{5-[(3,4-dimethoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

L303-3183 Screening compound: 1-(4-{5-[(3,4-dimethoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine
L303-3183 Screening compound: 1-(4-{5-[(3,4-dimethoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L303-3183
1-(4-{5-[(3,4-dimethoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L303-3183

Molecular Formula

C27H32N4O6S (C27 H32 N4 O6 S)

Compound Name

1-(4-{5-[(3,4-dimethoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

IUPAC name

1-(4-{5-[(34-dimethoxyphenyl)methyl]-124-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

SMILES

COc(ccc(Cc1nc(-c(cc2)ccc2S(N(CC2)CCC2C(N2CCCC2)=O)(=O)=O)no1)c1)c1OC

InChI

InChI=1S/C27H32N4O6S/c1-35-23-10-5-19(17-24(23)36-2)18-25-28-26(29-37-25)20-6-8-22(9-7-20)38(33,34)31-15-11-21(12-16-31)27(32)30-13-3-4-14-30/h5-10,17,21H,3-4,11-16,18H2,1-2H3

InChI Key

GLXXEPIYVWBWLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243089

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

540.64

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.784

Distribution Coefficient, logD

3.784

Water Solubility, LogSw

-4.03

Polar Surface Area

95.296

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

-1.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

L303-3183 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L303-3183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L303-3183?
Check Price and Availability of L303-3183, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L303-3183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L303-3183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L303-3183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L303-3183 available by request