L309-1214 Screening compound: N-(4-chloro-2-methylphenyl)-4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

L309-1214 Screening compound: N-(4-chloro-2-methylphenyl)-4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide
L309-1214 Screening compound: N-(4-chloro-2-methylphenyl)-4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L309-1214
N-(4-chloro-2-methylphenyl)-4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L309-1214

Molecular Formula

C22H21ClN4O5S (C22 H21 ClN4 O5 S)

Compound Name

N-(4-chloro-2-methylphenyl)-4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

IUPAC name

N-(4-chloro-2-methylphenyl)-4-[(5-cyclobutyl-124-oxadiazol-3-yl)methyl]-3-oxo-34-dihydro-2H-14-benzoxazine-6-sulfonamide

SMILES

Cc(cc(cc1)Cl)c1NS(c(cc1)cc(N2Cc3noc(C4CCC4)n3)c1OCC2=O)(=O)=O

InChI

InChI=1S/C22H21ClN4O5S/c1-13-9-15(23)5-7-17(13)26-33(29,30)16-6-8-19-18(10-16)27(21(28)12-31-19)11-20-24-22(32-25-20)14-3-2-4-14/h5-10,14,26H,2-4,11-12H2,1H3

InChI Key

KJHBTDIPECFBBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27244143

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.95

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.973

Distribution Coefficient, logD

3.763

Water Solubility, LogSw

-4.28

Polar Surface Area

97.211

Acid Dissociation Constant (pKa)

7.61

Base Dissociation Constant (pKb)

-3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L309-1214 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L309-1214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L309-1214?
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What is the minimum amount of L309-1214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L309-1214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L309-1214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L309-1214 available by request