L321-0124 Screening compound: ethyl 4-[1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-amido]piperidine-1-carboxylate

L321-0124 Screening compound: ethyl 4-[1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-amido]piperidine-1-carboxylate
L321-0124 Screening compound: ethyl 4-[1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-amido]piperidine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L321-0124
ethyl 4-[1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-amido]piperidine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L321-0124

Molecular Formula

C20H31N5O5 (C20 H31 N5 O5)

Compound Name

ethyl 4-[1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-amido]piperidine-1-carboxylate

IUPAC name

ethyl 4-[1-(13-dimethyl-26-dioxo-1236-tetrahydropyrimidin-4-yl)piperidine-4-amido]piperidine-1-carboxylate

SMILES

CCOC(N(CC1)CCC1NC(C(CC1)CCN1C(N(C)C(N1C)=O)=CC1=O)=O)=O

InChI

InChI=1S/C20H31N5O5/c1-4-30-20(29)25-11-7-15(8-12-25)21-18(27)14-5-9-24(10-6-14)16-13-17(26)23(3)19(28)22(16)2/h13-15H,4-12H2,1-3H3,(H,21,27)

InChI Key

ZWJCNOCWKGERIV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15123984

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.652

Distribution Coefficient, logD

0.652

Water Solubility, LogSw

-1.13

Polar Surface Area

82.643

Acid Dissociation Constant (pKa)

15.70

Base Dissociation Constant (pKb)

1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

70.00

L321-0124 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L321-0124 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L321-0124?
Check Price and Availability of L321-0124, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L321-0124 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L321-0124
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L321-0124
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L321-0124 available by request