L327-0866 Screening compound: 4-[5-(CYCLOHEXYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]-2-METHOXYPHENOL

L327-0866 Screening compound: 4-[5-(CYCLOHEXYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]-2-METHOXYPHENOL
L327-0866 Screening compound: 4-[5-(CYCLOHEXYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]-2-METHOXYPHENOL alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-0866
4-[5-(CYCLOHEXYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]-2-METHOXYPHENOL

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-0866

Molecular Formula

C24H34N6O2S (C24 H34 N6 O2 S)

Compound Name

4-[5-(CYCLOHEXYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]-2-METHOXYPHENOL

IUPAC name

n/a

SMILES

CCCN(CC1)CCN1c(s1)nn2c1nc(-c(cc1)cc(OC)c1O)c2NC1CCCCC1

InChI

InChI=1S/C24H34N6O2S/c1-3-11-28-12-14-29(15-13-28)24-27-30-22(25-18-7-5-4-6-8-18)21(26-23(30)33-24)17-9-10-19(31)20(16-17)32-2/h9-10,16,18,25,31H,3-8,11-15H2,1-2H3

InChI Key

SLJSGQVNBFZWHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245712

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.64

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.411

Distribution Coefficient, logD

3.541

Water Solubility, LogSw

-3.94

Polar Surface Area

62.379

Acid Dissociation Constant (pKa)

8.99

Base Dissociation Constant (pKb)

8.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.30

L327-0866 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-0866 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-0866?
Check Price and Availability of L327-0866, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-0866 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-0866
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-0866
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-0866 available by request