L327-1656 Screening compound: N-tert-butyl-6-[4-(diethylamino)phenyl]-2-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-1656 Screening compound: N-tert-butyl-6-[4-(diethylamino)phenyl]-2-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-1656 Screening compound: N-tert-butyl-6-[4-(diethylamino)phenyl]-2-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-1656
N-tert-butyl-6-[4-(diethylamino)phenyl]-2-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-1656

Molecular Formula

C23H35N7S (C23 H35 N7 S)

Compound Name

N-tert-butyl-6-[4-(diethylamino)phenyl]-2-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-tert-butyl-6-[4-(diethylamino)phenyl]-2-(4-methylpiperazin-1-yl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

CCN(CC)c(cc1)ccc1-c1c(NC(C)(C)C)n2nc(N3CCN(C)CC3)sc2n1

InChI

InChI=1S/C23H35N7S/c1-7-28(8-2)18-11-9-17(10-12-18)19-20(25-23(3,4)5)30-21(24-19)31-22(26-30)29-15-13-27(6)14-16-29/h9-12,25H,7-8,13-16H2,1-6H3

InChI Key

NDBSJYRVVBOPLD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245734

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.64

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.582

Distribution Coefficient, logD

3.857

Water Solubility, LogSw

-4.22

Polar Surface Area

39.993

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.50

L327-1656 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L327-1656 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-1656?
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What is the minimum amount of L327-1656 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-1656
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-1656
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-1656 available by request