L327-1938 Screening compound: N-tert-butyl-2-(4-cyclohexylpiperazin-1-yl)-6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-1938 Screening compound: N-tert-butyl-2-(4-cyclohexylpiperazin-1-yl)-6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-1938 Screening compound: N-tert-butyl-2-(4-cyclohexylpiperazin-1-yl)-6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-1938
N-tert-butyl-2-(4-cyclohexylpiperazin-1-yl)-6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-1938

Molecular Formula

C26H38N6S (C26 H38 N6 S)

Compound Name

N-tert-butyl-2-(4-cyclohexylpiperazin-1-yl)-6-(3,4-dimethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-tert-butyl-2-(4-cyclohexylpiperazin-1-yl)-6-(34-dimethylphenyl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

CC(C)(C)Nc1c(-c2cc(C)c(C)cc2)nc2sc(N(CC3)CCN3C3CCCCC3)nn12

InChI

InChI=1S/C26H38N6S/c1-18-11-12-20(17-19(18)2)22-23(28-26(3,4)5)32-24(27-22)33-25(29-32)31-15-13-30(14-16-31)21-9-7-6-8-10-21/h11-12,17,21,28H,6-10,13-16H2,1-5H3

InChI Key

ASJKADQQSJOJQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27644609

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.69

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.683

Distribution Coefficient, logD

5.866

Water Solubility, LogSw

-5.71

Polar Surface Area

36.873

Acid Dissociation Constant (pKa)

22.69

Base Dissociation Constant (pKb)

8.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.50

L327-1938 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-1938 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-1938?
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What is the minimum amount of L327-1938 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-1938
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-1938
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-1938 available by request