L327-3057 Screening compound: 1-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-3-cyclopentylpropan-1-one

L327-3057 Screening compound: 1-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-3-cyclopentylpropan-1-one
L327-3057 Screening compound: 1-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-3-cyclopentylpropan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-3057
1-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-3-cyclopentylpropan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-3057

Molecular Formula

C26H35FN6OS (C26 H35 FN6 OS)

Compound Name

1-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-3-cyclopentylpropan-1-one

IUPAC name

1-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}-3-cyclopentylpropan-1-one

SMILES

CC(C)(C)Nc1c(-c(cc2)ccc2F)nc2sc(N(CC3)CCN3C(CCC3CCCC3)=O)nn12

InChI

InChI=1S/C26H35FN6OS/c1-26(2,3)29-23-22(19-9-11-20(27)12-10-19)28-24-33(23)30-25(35-24)32-16-14-31(15-17-32)21(34)13-8-18-6-4-5-7-18/h9-12,18,29H,4-8,13-17H2,1-3H3

InChI Key

QDNBOYQFWVOXKR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642446

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.67

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.352

Distribution Coefficient, logD

5.352

Water Solubility, LogSw

-5.27

Polar Surface Area

50.267

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

3.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.70

L327-3057 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L327-3057 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-3057?
Check Price and Availability of L327-3057, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-3057 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-3057
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-3057
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-3057 available by request