L327-5530 Screening compound: N-tert-butyl-2-[4-(1-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-5530 Screening compound: N-tert-butyl-2-[4-(1-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-5530 Screening compound: N-tert-butyl-2-[4-(1-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-5530
N-tert-butyl-2-[4-(1-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-5530

Molecular Formula

C24H30N8OS (C24 H30 N8 OS)

Compound Name

N-tert-butyl-2-[4-(1-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-tert-butyl-2-[4-(1-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]-6-(3-methylphenyl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

CC(C)(C)Nc1c(-c2cc(C)ccc2)nc2sc(N(CC3)CCN3C(c3ccnn3C)=O)nn12

InChI

InChI=1S/C24H30N8OS/c1-16-7-6-8-17(15-16)19-20(27-24(2,3)4)32-22(26-19)34-23(28-32)31-13-11-30(12-14-31)21(33)18-9-10-25-29(18)5/h6-10,15,27H,11-14H2,1-5H3

InChI Key

UIWAMFHPQVMMPI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245939

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.753

Distribution Coefficient, logD

3.753

Water Solubility, LogSw

-3.78

Polar Surface Area

63.886

Acid Dissociation Constant (pKa)

22.69

Base Dissociation Constant (pKb)

4.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

L327-5530 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-5530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-5530?
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What is the minimum amount of L327-5530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-5530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-5530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-5530 available by request