L345-0060 Screening compound: [4-(4-fluorophenyl)piperazino](2,3,4,9-tetrahydro-1H-carbazol-1-yl)methanone

L345-0060 Screening compound: [4-(4-fluorophenyl)piperazino](2,3,4,9-tetrahydro-1H-carbazol-1-yl)methanone
L345-0060 Screening compound: [4-(4-fluorophenyl)piperazino](2,3,4,9-tetrahydro-1H-carbazol-1-yl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L345-0060
[4-(4-fluorophenyl)piperazino](2,3,4,9-tetrahydro-1H-carbazol-1-yl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L345-0060

Molecular Formula

C23H24FN3O (C23 H24 FN3 O)

Compound Name

[4-(4-fluorophenyl)piperazino](2,3,4,9-tetrahydro-1H-carbazol-1-yl)methanone

IUPAC name

1-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2349-tetrahydro-1H-carbazole

SMILES

O=C(C(CCC1)c2c1c(cccc1)c1[nH]2)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C23H24FN3O/c24-16-8-10-17(11-9-16)26-12-14-27(15-13-26)23(28)20-6-3-5-19-18-4-1-2-7-21(18)25-22(19)20/h1-2,4,7-11,20,25H,3,5-6,12-15H2/t20-/m1/s1

InChI Key

ZIZVHDAVAMKOGB-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD15124684

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.46

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.215

Distribution Coefficient, logD

4.214

Water Solubility, LogSw

-4.27

Polar Surface Area

30.278

Acid Dissociation Constant (pKa)

18.51

Base Dissociation Constant (pKb)

2.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.78

L345-0060 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L345-0060 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L345-0060?
Check Price and Availability of L345-0060, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L345-0060 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L345-0060
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L345-0060
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L345-0060 available by request