L346-0420 Screening compound: N-[5-(2-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]-4-(2-methylpropyl)benzene-1-sulfonamide

L346-0420 Screening compound: N-[5-(2-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]-4-(2-methylpropyl)benzene-1-sulfonamide
L346-0420 Screening compound: N-[5-(2-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]-4-(2-methylpropyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L346-0420
N-[5-(2-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]-4-(2-methylpropyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L346-0420

Molecular Formula

C26H37N5O3S (C26 H37 N5 O3 S)

Compound Name

N-[5-(2-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]-4-(2-methylpropyl)benzene-1-sulfonamide

IUPAC name

N-[5-(2-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]-4-(2-methylpropyl)benzene-1-sulfonamide

SMILES

CC(C)Cc(cc1)ccc1S(Nc(cc1C(N2C(C)CCCC2)=O)cnc1N1CCNCC1)(=O)=O

InChI

InChI=1S/C26H37N5O3S/c1-19(2)16-21-7-9-23(10-8-21)35(33,34)29-22-17-24(26(32)31-13-5-4-6-20(31)3)25(28-18-22)30-14-11-27-12-15-30/h7-10,17-20,27,29H,4-6,11-16H2,1-3H3/t20-/m0/s1

InChI Key

YRTMFOFZUDXCPR-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27247426

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

499.68

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.215

Distribution Coefficient, logD

2.737

Water Solubility, LogSw

-4.01

Polar Surface Area

81.305

Acid Dissociation Constant (pKa)

8.56

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

53.80

L346-0420 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L346-0420 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L346-0420?
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What is the minimum amount of L346-0420 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L346-0420
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L346-0420
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L346-0420 available by request