L351-0095 Screening compound: 2-(3-chlorophenyl)-5-({[(4-fluorophenyl)methyl](2-methylpropyl)amino}methyl)-1H,7H-pyrazolo[1,5-a]pyrimidin-7-one

L351-0095 Screening compound: 2-(3-chlorophenyl)-5-({[(4-fluorophenyl)methyl](2-methylpropyl)amino}methyl)-1H,7H-pyrazolo[1,5-a]pyrimidin-7-one
L351-0095 Screening compound: 2-(3-chlorophenyl)-5-({[(4-fluorophenyl)methyl](2-methylpropyl)amino}methyl)-1H,7H-pyrazolo[1,5-a]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L351-0095
2-(3-chlorophenyl)-5-({[(4-fluorophenyl)methyl](2-methylpropyl)amino}methyl)-1H,7H-pyrazolo[1,5-a]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L351-0095

Molecular Formula

C24H24ClFN4O (C24 H24 ClFN4 O)

Compound Name

2-(3-chlorophenyl)-5-({[(4-fluorophenyl)methyl](2-methylpropyl)amino}methyl)-1H,7H-pyrazolo[1,5-a]pyrimidin-7-one

IUPAC name

2-(3-chlorophenyl)-5-({[(4-fluorophenyl)methyl](2-methylpropyl)amino}methyl)-1H7H-pyrazolo[15-a]pyrimidin-7-one

SMILES

CC(C)CN(Cc(cc1)ccc1F)CC(N=C1N2NC(c3cccc(Cl)c3)=C1)=CC2=O

InChI

InChI=1S/C24H24ClFN4O/c1-16(2)13-29(14-17-6-8-20(26)9-7-17)15-21-11-24(31)30-23(27-21)12-22(28-30)18-4-3-5-19(25)10-18/h3-12,16,28H,13-15H2,1-2H3

InChI Key

HESGRXQGPZZPIZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124768

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.93

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.785

Distribution Coefficient, logD

4.681

Water Solubility, LogSw

-4.86

Polar Surface Area

44.885

Acid Dissociation Constant (pKa)

9.47

Base Dissociation Constant (pKb)

6.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L351-0095 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with L351-0095 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L351-0095?
Check Price and Availability of L351-0095, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L351-0095 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L351-0095
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L351-0095
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L351-0095 available by request