L369-0495 Screening compound: 3-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[4-(morpholin-4-yl)phenyl]benzamide

L369-0495 Screening compound: 3-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[4-(morpholin-4-yl)phenyl]benzamide
L369-0495 Screening compound: 3-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[4-(morpholin-4-yl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L369-0495
3-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[4-(morpholin-4-yl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L369-0495

Molecular Formula

C27H24FN5O2 (C27 H24 FN5 O2)

Compound Name

3-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[4-(morpholin-4-yl)phenyl]benzamide

IUPAC name

3-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[4-(morpholin-4-yl)phenyl]benzamide

SMILES

O=C(c1cccc(Nc(nc2)ncc2-c2cccc(F)c2)c1)Nc(cc1)ccc1N1CCOCC1

InChI

InChI=1S/C27H24FN5O2/c28-22-5-1-3-19(15-22)21-17-29-27(30-18-21)32-24-6-2-4-20(16-24)26(34)31-23-7-9-25(10-8-23)33-11-13-35-14-12-33/h1-10,15-18H,11-14H2,(H,31,34)(H,29,30,32)

InChI Key

WQRGVVKTVUKYFG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27248534

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.828

Distribution Coefficient, logD

4.827

Water Solubility, LogSw

-4.68

Polar Surface Area

64.080

Acid Dissociation Constant (pKa)

11.20

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L369-0495 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Proline Kinase Library (2105 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L369-0495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L369-0495?
Check Price and Availability of L369-0495, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L369-0495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L369-0495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L369-0495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L369-0495 available by request